PIPages
Labs

Gregory DiGirolamo

University of Massachusetts Chan Medical School, MA·Psychology

Radiologists can miss up to half of hard-to-see lung nodules, the small spots on chest scans that may be early lung cancer. Yet trained experts often process more than they consciously notice.

Fields

Psychology

Medicine & Clinical Research

Computer Science

Topics

lung cancer

lung nodules

nodule detection

Grants
1 known grant, through Jul 2027

What they work on

  1. Test how well eye-tracking biomarkers of non-conscious detection, recorded while radiologists search chest CTs, can train and refine machine learning models to find missed lung nodules.
  2. Measure whether feeding back the locations that the ML models flag as missed nodules increases the number of nodules radiologists detect.
  3. Determine whether the trained ML models generalize to new radiologists reading a new set of chest CT images.

More about the research

More than 80% of lung cancer patients are diagnosed at an advanced stage, and the 5-year survival rate is 21%. This project asks whether a radiologist's non-conscious detection of a nodule can be captured and used to catch nodules that would otherwise be missed.

Why it matters

Catching small lung nodules that radiologists currently miss could lead to earlier lung cancer diagnosis, when treatment is more likely to succeed. Machine learning tools that use radiologists' own non-conscious detection could reduce diagnostic errors in chest CT reading and may help raise lung cancer's 21% five-year survival rate.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Increasing Nodule Detection in Lung Cancer by Non-Conscious Detection of "Missed" Nodules and Machine Learning

NIH · May 2022 – Jul 2027

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Daniela Raicu

DePaul University, IL·Computer Science

Develop a Semantic Deep-learning Neural Network (SDNN), a deep-learning model enhanced with knowledge of what visual features mean, that generates visual patterns and example images resembling the concepts radiologists use to read lung nodules.

The school

University of Massachusetts Chan Medical School: 29 labs on PI Pages, $350M a year on research, 55 research doctorates a year.

More about University of Massachusetts Chan Medical School

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