PIPages
Labs

Alejandro Ribeiro

University of Pennsylvania, PA·Engineering

Generative artificial intelligence systems can write text, draw images and design molecules, but they produce whatever their training data taught them, including biases, unsafe content and plain falsehoods. The common problem across both projects here is control: how to steer a large pretrained generative model so its output satisfies requirements a user cares about, and how to do so with mathematical guarantees rather than trial and error.

Fields

Engineering

Computer Science

Mathematics & Statistics

Topics

generative AI

alignment

large language models

Grants
2 known grants, through Sep 2028

What they work on

  1. Develop optimization and statistical foundations for aligning generative models by exploiting that the problem is strongly concave in distribution space even though it is highly nonconvex in the parameters of deep networks and transformers.
  2. Formulate alignment as a reinforcement learning problem with a known value function, and show how this simplification yields tractable algorithms for enforcing fairness, safety, robustness and truthfulness constraints.
  3. Build a unified treatment of alignment for large language models and generative diffusion models, both posed as matching a generative model to user requirements given a pretrained reference.
  4. Construct discrete diffusion processes that generate graphs by progressively adding or removing edges, reducing the combinatorial cost of graph-space search compared with the Gaussian diffusion used for images and audio.
  5. Train generative graph models at small scale and transfer them to much larger graphs using graphon and manifold abstractions and corresponding graphon and manifold neural network architectures.
  6. Incorporate user-specified structural constraints into graph generation and apply the resulting models to molecular graphs that mimic molecules with known properties for AI-aided drug discovery.

More about the research

One project builds the optimization theory of this steering problem for language and image models; the other extends generative modeling to graphs, where the requirements are structural constraints on the relationships being generated.

Why it matters

Generative AI tools are being built into everyday software while still reproducing biases, unsafe outputs and false content. A rigorous theory of alignment could give developers principled ways to enforce fairness, safety and truthfulness requirements when adapting public pretrained models. Scalable constrained graph generation could speed AI-aided drug discovery by proposing molecules with target properties, with likely effects in communications, robotics, circuit design and health.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

MFAI: Mathematical Foundations of Alignment in Generative Artificial Intelligence

NSF · Oct 2025 – Sep 2028

NSF-SNSF: Generative Graph Models at Scale: Discrete Diffusion, Transferability and Requirements

NSF · Oct 2024 – Sep 2027

Closest labs

Yusu Wang

University of California-San Diego, CA·Computer Science

Explain why trained flow-based and diffusion generative models generalize better than the theoretically optimal solution predicts, using geometry, ODE analysis, manifold learning and deep learning theory, to enable controlled generation of novel samples.

Zaid Harchaoui

University of Washington, WA·Computer Science

Identify the mathematical quantities that drive generalization in frontier generative models, including large language models, using frameworks from probability theory, variational analysis, mathematical statistics and information theory.

Faez Ahmed

Massachusetts Institute of Technology, MA·Engineering·Early-career

Develop diffusion models, generative AI that builds outputs by removing noise step by step, that learn from the full history of design optimization runs rather than only final optimized designs, to generate more precise engineering designs.

The school

University of Pennsylvania: 90 labs on PI Pages, $2.2B a year on research, 750 research doctorates a year.

More about University of Pennsylvania

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