Christopher Palmer
University of Montana, MT·Chemistry
Liquid chromatography is a standard tool for working out what is in a mixture. It separates molecules by how strongly they stick to a packed material, called the stationary phase, as liquid flows past.
- Fields
Chemistry
Materials Science
- Topics
halogen bonding
liquid chromatography
stationary phase
- Grants
- 1 known grant, through Jul 2027
What they work on
- Design and synthesize liquid chromatography stationary phases that retain molecules through halogen bonding, using well-characterized halogen bond donors in monodentate (one-site) and bidentate (two-site) forms.
- Characterize the structure and properties of the new halogen bond-donating stationary phase materials.
- Measure the chromatographic performance and separation selectivity of halogen bonding phases, and compare them with traditional separation mechanisms, as a first step toward analyzing pharmaceuticals, peptides, and proteins.
More about the research
It is used to check food and drug safety and in environmental analysis, clinical medicine, defense, and materials engineering. Most stationary phases rely on familiar attractions, such as oil-loving or charge-based interactions. Mixtures that these attractions cannot separate well remain a challenge. This project, a collaboration between the Palmer and Berryman groups, explores a different attraction: halogen bonding.
Why it matters
New halogen bonding materials could give analytical chemists separation selectivity that existing columns lack. This could help laboratories that check the quality and safety of foods and drugs, monitor the environment, or analyze clinical samples. In the future, it could also improve the separation of pharmaceuticals, peptides, and proteins.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Preston Snee
University of Illinois Chicago, IL·Chemistry
Synthesize quantum dots with functional organic shells, and modify chromatography stationary phases with complementary DNA strands, to control the attractive (enthalpic) interactions during separation.
Wenqi Liu
University of South Florida, FL·Chemistry·Early-career
Design and synthesize acyclic (open-chain) receptors that use ion-dipole and electrostatic interactions to bind lithium ions selectively over competing metal ions, and measure their binding in solution.
Viktor Zhdankin
University of Minnesota-Duluth, MN·Chemistry
Develop pseudocyclic arylbenziodoxaboroles, iodine–boron compounds, as benzyne precursors and as efficient electrophilic arylating reagents that work under neutral, aqueous conditions.
The school
University of Montana: 3 labs on PI Pages, $144M a year on research, 74 research doctorates a year.
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