PIPages
Labs

Liyun Wang

University of Delaware, DE·Biomedical Engineering

Bones, cartilage, tendons and muscles stay healthy partly because of the physical forces they feel and partly because of chemical signals between cells. Understanding how these cues keep tissues working, and what goes wrong in disease, requires tools that can image and test tissues at many scales, from the whole body down to molecules.

Fields

Biomedical Engineering

Physiology

Topics

musculoskeletal research

bone

cartilage

Grants
1 known grant, through May 2031

What they work on

  1. Expand the research core's capabilities in multimodal imaging, preclinical animal models, biomechanical testing and histology to support musculoskeletal studies from whole-body to molecular scales.
  2. Deliver hands-on training and streamlined data integration so center researchers can use the core's imaging and biomechanics services effectively.
  3. Expand partnerships with other institutional research centers and build a sustainable business framework so the core continues beyond the current award.

More about the research

This grant supports a shared research core within a musculoskeletal research center that provides those tools to many investigators.

Why it matters

Musculoskeletal problems affect the bones, joints and muscles that people rely on to move. By giving researchers shared access to imaging, mechanical testing, animal models and tissue analysis, the core could speed studies of why these tissues fail and help investigators develop new strategies to restore musculoskeletal health.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Delaware Center for Musculoskeletal Research, Phase II Research Core

NIH · Feb 2021 – May 2031

Closest labs

X. Lucas Lu

University of Delaware, DE·Biomedical Engineering

Determine whether statin use is linked to lower rates of osteoarthritis in the Delaware population, using a retrospective cohort study of existing health records.

Anuradha Subramanian

University of Alabama in Huntsville, AL·Biomedical Engineering

Demonstrate whether continuous low-intensity ultrasound (cLIUS) drives mesenchymal stromal cells to form cartilage even in a pro-inflammatory environment, using RNA sequencing to profile the transcriptome and identify the pathways involved.

Nathaniel Dyment

University of Pennsylvania, PA·Biomedical Engineering

Measure how long the hedgehog pathway activator SAG is released from BiLDS scaffolds and whether it stays biologically active, using an in vitro release study.

The school

University of Delaware: 22 labs on PI Pages, $466M a year on research, 298 research doctorates a year.

More about University of Delaware

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