Jason D Robinson
University of Texas MD Anderson Cancer Center, TX·Medicine & Clinical Research
Smoking kills more than 480,000 Americans early each year. Many smokers try to quit, but most relapse, often within two weeks.
- Fields
Medicine & Clinical Research
Public Health & Epidemiology
Psychology
- Topics
smoking cessation
tobacco
nicotine dependence
- Grants
- 2 known grants, through Dec 2028
What they work on
- Compare quit rates after six weeks of varenicline versus dual nicotine replacement therapy (patch plus lozenge) among 2,000 Texas smokers in a virtually delivered SMART trial, confirming abstinence by breath carbon monoxide.
- Test whether smokers who fail initial treatment do better by continuing, switching medications or augmenting therapy (higher dose or added drugs such as bupropion), measuring abstinence, craving, withdrawal and mood.
- Characterize how switching from cigarettes to e-cigarettes for six months changes product use, acceptability, reward and dependence in 330 older smokers at high lung-cancer risk who do not plan to quit.
- Measure changes in blood markers of inflammation and oxidative stress, and in metabolomic profiles (broad sets of small molecules), when high-risk smokers switch from cigarettes to e-cigarettes, and identify factors that shape these effects.
More about the research
Little evidence tells doctors what to do when a first quit attempt fails, and many older heavy smokers do not want to quit at all. This research tests practical medication strategies for people trying to quit. It also asks whether switching to e-cigarettes could reduce harm for older smokers at high risk of lung cancer who will not quit.
Why it matters
Smokers who fail a first quit attempt could get clearer, personalized guidance on whether to stay on, switch or strengthen their medication. Virtual delivery could reach rural, uninsured and low-income smokers. Evidence on how switching to e-cigarettes changes inflammation and other health markers in older smokers at high lung-cancer risk could inform FDA regulatory science and public health policy on harm reduction.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Kathryn Taylor
Georgetown University, DC·Public Health & Epidemiology
Compare electronic quitline referral against a centralized health-system phone counseling plus nicotine replacement program for lung screening patients, measuring biologically verified quitting at 3 and 6 months.
Michael Kotlyar
University of Minnesota, MN·Public Health & Epidemiology
Test whether people who smoke menthol cigarettes take up nicotine pouches more than medicinal nicotine, using a randomized 6-week study of 252 participants in an experimental marketplace.
Elias Klemperer
University of Vermont, VT·Public Health & Epidemiology
Test whether very low nicotine content cigarettes reduce cigarettes smoked per day and cigarette dependence among adult dual users of cigarettes and e-cigarettes, in a 12-week double-blind randomized trial.
The school
University of Texas MD Anderson Cancer Center: 23 labs on PI Pages, $1.4B a year on research.
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