Debarshi Roy
Alcorn State University, MS·Biomedical Engineering
When a tiny engineered particle or polymer enters the body, proteins and immune cells react to it almost at once. Those reactions decide whether a new material is safe and whether it works as a drug carrier or tissue scaffold.
- Fields
Biomedical Engineering
Materials Science
Chemistry
- Topics
biomaterials
nanomaterials
nanoparticles
- Grants
- 1 known grant, through Jul 2028
What they work on
- Engineer the protein corona, the layer of body proteins that coats a nanoparticle, on biomimetic materials to control how the particles interact with the immune system.
- Design polymer nanocarriers that bind nucleic acids such as DNA or RNA tightly and then release them efficiently, guided by physical and chemical characterization and computer modeling.
- Develop bioinspired polymer scaffolds that support tissue regeneration while resisting infection by pathogens.
- Establish general structure-property-function rules for biomaterials by combining synthesis, characterization, and computational modeling in a shared design loop across the NIEC consortium.
More about the research
Biomaterials are materials designed to interact with living systems. Learning how their structure controls their behavior in the body is a key step toward using them in the clinic. This grant also links that goal to health disparities in Mississippi and the surrounding region.
Why it matters
This work could help researchers design nanomaterials and polymers that are safe enough for clinical use. Examples include carriers that deliver genetic medicines and scaffolds that rebuild tissue while resisting infection. The consortium focuses on health disparities in Mississippi and the surrounding region. It also aims to support local biotech startups and the development of intellectual property, which could create high-tech jobs in the state.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Jordan Green
Johns Hopkins University, MD·Biomedical Engineering
Design and synthesize nanoparticles and biomaterials with tuned chemistry, physical properties and biologic surface coatings that deliver nucleic acids into specific immune cells, inside and outside the body.
Kagya Amoako
University of New Haven, CT·Biomedical Engineering
Formulate and characterize a library of lipid nanoparticles (LNPs) varying in size, charge, PEGylation (a polyethylene glycol coating), and surface ligand chemistry, and determine how these properties change binding to platelets, white cells, red cells, and plasma proteins.
Ashish Kulkarni
University of Massachusetts, MA·Biomedical Engineering·Early-career
Engineer a library of polymeric nanoparticles whose surface and core properties are varied one at a time, to establish structure–property–function relationships for inflammasome activation, the immune complex that drives inflammatory signaling.
The school
Alcorn State University: 1 labs on PI Pages, $15M a year on research.
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