Taylor Triolo
University of Colorado Denver/Anschutz Medical Campus, CO·Medicine & Clinical Research·Early-career
In type 1 diabetes, the pancreas loses its insulin-making beta cells. People who keep some of their own beta cell function have better blood sugar control and fewer complications.
- Fields
Medicine & Clinical Research
Genetics
Physiology
- Topics
type 1 diabetes
beta cells
beta cell function
- Grants
- 1 known grant, through Jul 2027
What they work on
- Analyze whether baseline markers of beta cell function and stress predict C-peptide preservation during the partial remission, or "honeymoon," period in patients newly diagnosed with type 1 diabetes.
- Evaluate whether pre-specified type 1 diabetes SNPs, common DNA variants, are associated with C-peptide preservation during partial remission, using a longitudinal new-onset cohort and genomic data.
- Test whether SNPs linked to C-peptide preservation predict insulin use and C-peptide levels in chronic pancreatitis patients after total pancreatectomy with islet autotransplantation (TPIAT).
More about the research
Yet this varies widely from person to person, and the role of genetics in this variation is poorly understood. This career development project asks which genes and blood markers predict how well beta cell function is preserved. It studies two groups: people newly diagnosed with type 1 diabetes and people with chronic pancreatitis who received a beta cell transplant.
Why it matters
Future type 1 diabetes treatments aim to protect remaining beta cells or replace them through transplantation. Finding genetic and biomarker predictors of preserved C-peptide could support more personalized therapies. It could also help predict outcomes for people with type 1 diabetes and for chronic pancreatitis patients receiving islet transplants.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Howard Davidson
University of Colorado Denver/Anschutz Medical Campus, CO·Medicine & Clinical Research
Define and validate classifiers that predict fast or slow type 1 diabetes progression in the first two years after onset from a single baseline blood draw taken 3–6 months post-diagnosis.
Kendra Vehik
University of South Florida, FL·Public Health & Epidemiology
Identify early-life plasma microRNA signatures that predict future type 1 diabetes, using longitudinal blood samples from the TEDDY cohort of genetically at-risk children.
Hirotake Komatsu
University of California-San Francisco, CA·Biomedical Engineering
Build human islet organoids about 5 mm thick by layering parylene microcapillary mesh that carries oxygen from flowing culture medium, testing whether a dynamic culture system keeps the organoid core alive past the usual diffusion limit.
The school
University of Colorado Denver/Anschutz Medical Campus: 41 labs on PI Pages, $766M a year on research, 205 research doctorates a year.
More about University of Colorado Denver/Anschutz Medical Campus
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