PIPages
Labs

Najib Majaj

New York University, NY·Neuroscience

Most neuroscience experiments study animals held still in front of a screen, on the assumption that what the brain does there reflects real life. That assumption has rarely been tested.

Fields

Neuroscience

Psychology

Computer Science

Topics

systems neuroscience

foraging

spatial navigation

Grants
1 known grant, through Mar 2028

What they work on

  1. Compare neural computations and behavioral algorithms in macaques foraging head-free in a foraging room with those during head-fixed navigation in virtual reality, to test whether restrained lab conditions differ from naturalistic ones.
  2. Record simultaneously from posterior parietal, prefrontal, retrosplenial and entorhinal cortex and the hippocampus to track how these connected areas interact during foraging and navigation.
  3. Use behavioral models and theory to infer monkeys' internal states, such as beliefs and memories, during goal-driven foraging among three resource patches, and identify how these states are represented in the brain.
  4. Regress neuronal activity against task-relevant variables to find neural subspaces encoding them, and test the roles of hippocampal, frontal and parietal areas in different components of foraging.

More about the research

This project asks how the brain supports foraging, the search for food in a changing world, and whether brain activity in freely moving monkeys differs from activity in restrained monkeys doing similar tasks. Any differences would matter for how the whole field reads laboratory results.

Why it matters

Testing whether brain activity in restrained laboratory animals matches activity during natural behavior could change how neuroscience experiments are designed and interpreted. Revealing the general strategies brains use for naturalistic tasks like foraging and navigation could inform psychiatry and the design of artificial intelligence systems.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Computational Dynamics in Neural Populations of Freely Foraging vs. Restrained Monkeys

NIH · Apr 2022 – Mar 2028

Closest labs

Christopher D Harvey

Harvard University, MA·Neuroscience

Map effective connectivity among functionally identified neurons in the posterior parietal cortex during a virtual-reality navigation decision task, using cellular-resolution optogenetics to stimulate small groups of neurons and testing wiring motifs predicted by decision-making theories.

Jean-Marc Fellous

University of California-San Diego, CA·Neuroscience

Characterize whether ventral hippocampal place cells, whose firing zones are too broad to distinguish locations in small arenas, carry useful position information in very large environments, by recording dorsal and ventral hippocampus simultaneously in rats.

Noah John Cowan

Johns Hopkins University, MD·Neuroscience

Develop control-theory and machine-learning models to explain how and why animals switch between fast exploratory active sensing and slower goal-directed task control, based on internal estimates of sensory uncertainty.

The school

New York University: 72 labs on PI Pages, $1.5B a year on research, 540 research doctorates a year.

More about New York University

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