PIPages
Labs

Megan Valentine

University of California-Santa Barbara, CA·Materials Science

Living cells change shape, move and apply force on their own schedule, guided by internal biological clocks and circuits. Man-made 'active' materials usually need an outside trigger to do anything.

Fields

Materials Science

Biophysics

Engineering

Topics

living materials

biotic-abiotic materials

programmable materials

Grants
1 known grant, last ended Sep 2026

What they work on

  1. Build layered materials that pair synthetic hydrogels with living cytoskeleton composites, protein filament networks, fitted with cellular timing circuits that make material-modifying proteins on a set schedule.
  2. Create a proof-of-concept gap-closing micro-actuator that closes under light and reopens on its own at times and locations programmed into embedded cell circuits.
  3. Map how material recipes relate to structure, mechanics and function through design-build-test-learn cycles combining multi-scale modeling with high-throughput mechanical and structural characterization.
  4. Assemble and publicly share a formulation-property database for programmable living materials to support the Materials Genome Initiative community.

More about the research

This collaborative project, run by a team of physicists, biologists and engineers across five campuses, aims to build materials that behave more like living things. These materials would do work and move on a programmed timetable, without outside control.

Why it matters

Materials that move and reshape themselves on a programmed schedule could eventually enable self-healing infrastructure, self-regulating delivery vehicles, self-propelled materials, micro-robots and programmable dynamic prosthetics. Public recipe-property libraries could help other materials researchers design and make such living materials.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Collaborative Research: DMREF: Living biotic-abiotic materials with temporally programmable actuation

NSF · Oct 2021 – Sep 2026

Closest labs

Martin Harmer

Lehigh University, PA·Materials Science

Discover new sodium-ion conducting oxide ceramics by combining ultra-high-temperature synthesis, which sinters materials in about 10 seconds, with first-principles data-driven computation and high-throughput measurements.

Gannon Jennings

Vanderbilt University, TN·Engineering

Identify, synthesize and test new polymer membranes that separate water from polar organic solvents by pervaporation, using ring-opening metathesis polymerization and spin coating.

Vivek Shenoy

University of Pennsylvania, PA·Biomedical Engineering

Characterize and engineer proteins and nanostructures that respond to piconewton forces and nanometer displacements, to build mechano-biological reagents and materials.

The school

University of California-Santa Barbara: 17 labs on PI Pages, $303M a year on research, 403 research doctorates a year.

More about University of California-Santa Barbara

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