PIPages
Labs

Swathi Kiran

Boston University, MA·Neuroscience

People who speak two languages vary widely in how well they handle each one. Strokes and dementia can disrupt those abilities in very different ways.

Fields

Neuroscience

Psychology

Medicine & Clinical Research

Topics

bilingualism

aphasia

semantic dementia

Grants
1 known grant, through Aug 2028

What they work on

  1. Characterize the lexical and semantic impairments observed in bilingual post-stroke aphasia and bilingual semantic dementia, and explain how they arise, using the BILEX computational model's maps and connections.
  2. Extend BILEX simulations over time to explain how bilingual language abilities recover after stroke and decline in dementia, accounting for age of acquisition, language use and exposure.
  3. Add subcortical conditional routing mechanisms to BILEX to model how bilingual speakers select and control their languages, and how interference arises in neurological disorders.

More about the research

Cases of both conditions are rising, and the US Hispanic population, many of them Spanish-English bilinguals, is growing and aging. That makes it urgent to understand how bilingual language breaks down and recovers. Capturing all of this variation directly would require studying hundreds of patients over time, which is impractical. This project instead proposes computer simulations of the bilingual language system.

Why it matters

Spanish-English bilingual older adults with stroke-related aphasia or dementia need language assessment and therapy matched to how their two languages are affected. Mechanistic models of impairment, recovery and decline could help guide future treatments for these growing patient populations, including cases for which no patient data yet exist.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Computational modeling of language impairment and control in bilingual individuals with post-stroke aphasia and neurodegenerative disorders

NIH · Sep 2023 – Aug 2028

Closest labs

William Graves

Rutgers University-Newark, NJ·Psychology

Develop neural network accounts of post-stroke dyslexias by lesioning a model that links spelling, sound and meaning, then re-training it to simulate damage and recovery in groups and individual patients.

Maria V. Ivanova

University of California-Berkeley, CA·Medicine & Clinical Research

Test whether high-intensity exercise improves language, cognition, movement and emotional well-being in 110 stroke survivors with aphasia, compared with a matched low-intensity exercise control in a randomized trial.

Eleonora Rossi

University of Florida, FL·Psychology

Test whether the composition and structure of heritage Spanish speakers' personal social networks, mapped through network interviews, predict their written and oral fluency in Spanish and English.

The school

Boston University: 26 labs on PI Pages, $784M a year on research, 630 research doctorates a year.

More about Boston University

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