Muralidharan Jayaraman
University of Oklahoma-Health Sciences Center, OK·Medicine & Clinical Research
Cancer research depends on carefully analyzing cells and tissues, from tumor samples to cultured cell lines, and on making sure those samples are what researchers think they are. This grant supports the Cell and Tissue Analysis (CTA) Core, a shared facility that provides these services, expertise and instruments to cancer investigators in a research center program (COBRE) and to other cancer researchers in Oklahoma.
- Fields
Medicine & Clinical Research
Biology
- Topics
cancer research
core facility
tissue microarray
- Grants
- 1 known grant, through Jun 2029
What they work on
- Provide tissue microarray construction, histochemical staining and immunohistochemistry on paraffin-embedded and frozen tissues to support cancer biology and diagnostics research.
- Offer RNAscope, BaseScope and miRNAscope in situ hybridization to detect specific RNA molecules directly within cancer tissue samples.
- Support cell-based studies through circulating tumor cell isolation, Seahorse metabolic flux analysis and hypoxic chamber experiments for cancer investigators.
- Ensure research integrity by authenticating cell lines with Short Tandem Repeat (STR) profiling and testing cultures for mycoplasma contamination.
More about the research
Established in 2012, it is described as the only facility of its kind in the state.
Why it matters
Reliable tissue staining, RNA detection, metabolic assays and cell-line authentication help cancer researchers in Oklahoma produce trustworthy results about cancer biology, treatment and diagnosis. Shared access to these tools supports studies that could inform new cancer therapies and diagnostics.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Brent Harris
Georgetown University, DC·Medicine & Clinical Research
Collect and distribute clinically annotated human biospecimens, including fresh, frozen, and formalin-fixed paraffin-embedded tissue and selected biofluids from a bank spanning 15,440 patients, for translational cancer research across the consortium.
Zuhair Ballas
University of Iowa, IA·Medicine & Clinical Research
Provide cancer researchers with high-speed cell sorting, multi-parameter analysis and purification of specific cell subsets for basic and translational studies at the Holden Comprehensive Cancer Center.
Jason Mills
Baylor College of Medicine, TX·Medicine & Clinical Research
Provide reliable tissue processing and histopathology services, including embedding, microtomy, staining and histochemistry, to characterize disease features in human and animal gastrointestinal tissues.
The school
University of Oklahoma-Health Sciences Center: 11 labs on PI Pages, $474M a year on research, 31 research doctorates a year.
Reach out
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