Francisco Pasquel
Emory University, GA·Medicine & Clinical Research
More than 8 million people with diabetes are hospitalized each year in the United States. When their blood sugar is poorly controlled during a hospital stay, they face a much higher risk of bad outcomes.
- Fields
Medicine & Clinical Research
Public Health & Epidemiology
- Topics
diabetes
hospital hyperglycemia
hypoglycemia
- Grants
- 1 known grant, through Feb 2027
What they work on
- Test in a multicenter randomized trial whether automated insulin delivery with a disposable patch pump and remote real-time continuous glucose monitoring increases time in target glucose range (70–180 mg/dL) compared with daily insulin injections plus CGM in hospitalized adults.
- Assess the safety of inpatient automated insulin delivery by measuring time spent in hypoglycemia (below 54 mg/dL), with remote nursing monitoring and electronic health record documentation of sensor glucose.
- Establish methods for checking CGM accuracy and recording sensor glucose values in the electronic health record during hospital use of diabetes technology.
- Identify infrastructure needs and factors affecting adoption of inpatient automated insulin delivery through surveys and semi-structured interviews with patients, nurses and hospital staff.
More about the research
The usual approach, several insulin injections a day, often fails to keep glucose in a safe range. Automated insulin delivery (AID), in which a glucose sensor and an insulin pump work together and adjust doses automatically, has helped in European studies. However, it is unclear how to use it safely, affordably and at scale in U.S. hospitals.
Why it matters
Hospitalized patients with diabetes often cannot keep blood sugar under control, which puts them at risk of serious harm. Showing that disposable, remotely monitored automated insulin delivery can keep glucose in range safely could improve inpatient diabetes care. This includes patients in isolation and those with type 1 or steroid-induced diabetes. The resulting care algorithms could help other health systems adopt the approach.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Mark Deboer
University of Virginia, VA·Medicine & Clinical Research
Test whether adding real-time tracking of insulin sensitivity to the APEX automated insulin system lowers hypoglycemia risk (Low Blood Glucose Index) during and after exercise, in a randomized crossover hotel study.
Jenise Wong
University of California-San Francisco, CA·Medicine & Clinical Research
Partner with Latinx teens with type 1 diabetes, their families and clinicians through focus groups and semi-structured interviews to adapt a virtual peer group model that promotes starting and continuing diabetes device use.
Morgana Mongraw-Chaffin
Wake Forest University, NC·Medicine & Clinical Research
Strengthen consultation on using continuous glucose monitors in diabetes research, including advanced study design, analytic methods and practical concerns.
The school
Emory University: 70 labs on PI Pages, $1.2B a year on research, 286 research doctorates a year.
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