PIPages
Labs

Lee Kehoe

University of Rochester, NY·Medicine & Clinical Research·Early-career

Caring for an older relative who has both dementia and advanced cancer is extremely stressful. The caregiver's distress and the patient's distress can also feed off each other.

Fields

Medicine & Clinical Research

Psychology

Public Health & Epidemiology

Topics

caregivers

caregiver distress

Alzheimer's disease

Grants
1 known grant, through Apr 2030

What they work on

  1. Evaluate whether 8 weekly sessions of Dyadic Life Review therapy, added to usual care, reduce psychological distress in caregivers of older adults with AD/ADRD and stage III–IV cancer, in a 60-dyad randomized trial.
  2. Test whether Dyadic Life Review works by improving relationship quality and dyadic coping, the ways caregiver and patient handle stress together, measured by caregiver self-report.
  3. Explore which patient characteristics, such as cognitive status and relationship type, are linked to how much caregivers benefit from Dyadic Life Review.

More about the research

This project tests a talk-based therapy that patient and caregiver do together, to see whether it eases that strain.

Why it matters

Family caregivers of older adults living with both dementia and advanced cancer face a double burden and high psychological distress. If Dyadic Life Review proves effective, it could become a structured, scalable way for clinical teams in geriatric oncology and dementia care to reduce caregiver distress, strengthen relationships, and improve quality of life for both members of these families.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Efficacy of Dyadic Life Review Therapy for Distressed Caregivers of Older Patients with Alzheimer's Disease and Related Dementias (ADRD) and Advanced Cancer

NIH · Aug 2026 – Apr 2030

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David Ziegler

University of California-San Francisco, CA·Psychology

Determine the minimum effective dose of MediTrain, a closed-loop digital meditation program that trains focused attention, for improving cognitive control and reducing stress in older adults, using a nationwide mobile randomized controlled trial of 3,240 participants.

Yeonsu Song

University of California-Los Angeles, CA·Medicine & Clinical Research

Culturally adapt an existing cognitive behavioral therapy for insomnia (CBTI) program for older Korean immigrants with limited English, using established cultural adaptation strategies and feedback from community stakeholders and participants.

The school

University of Rochester: 38 labs on PI Pages, $492M a year on research, 308 research doctorates a year.

More about University of Rochester

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