PIPages
Labs

Michael Conte

University of California-San Francisco, CA·Medicine & Clinical Research

More than 37 million people in the United States have diabetes, and about 15–20% of them will develop a diabetic foot ulcer, an open wound on the foot. These ulcers heal slowly, often return, and frequently lead to lower-limb amputation, which affects about 150,000 Americans each year.

Fields

Medicine & Clinical Research

Public Health & Epidemiology

Topics

diabetic foot ulcer

diabetes

wound healing

Grants
1 known grant, through Dec 2027

What they work on

  1. Recruit diverse patients with diabetic foot ulcers from UCSF Medical Center, Zuckerberg San Francisco General Hospital and Bay Area podiatry clinics into Diabetic Foot Consortium biomarker trials, including those testing c-Myc and transepidermal water loss.
  2. Launch a common master protocol that enrolls all patients with an open diabetic foot ulcer to examine standard-of-care practices and test new candidate biomarkers of healing.
  3. Collect social determinants of health data, such as economic and social conditions, from patients with diabetic foot ulcers and examine how they relate to healing and other outcomes.

More about the research

Better ways to predict healing and guide care are badly needed. This clinical research unit at UCSF is one of six original centers in the national Diabetic Foot Consortium, a multi-center network focused on developing and validating biomarkers, measurable signs that can predict how a wound will heal.

Why it matters

Diabetic foot ulcers cause great suffering, frequent amputations and high healthcare costs. By helping validate biomarkers that predict healing, studying current standard care, and measuring how social factors affect outcomes, this work could help clinicians treat ulcers more effectively and reduce amputations for patients with diabetes in the Bay Area and nationwide.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

UCSF Diabetic Foot Clinical Research Unit

NIH · Sep 2018 – Dec 2027

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Suzanne Mitchell

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The school

University of California-San Francisco: 89 labs on PI Pages, $2.1B a year on research, 164 research doctorates a year.

More about University of California-San Francisco

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