Michael Stein
Boston University, MA·Medicine & Clinical Research
Opioid use disorder (OUD), the medical condition of compulsive opioid use, and unhealthy drinking among people living with HIV are both cases where good treatments exist but many people do not benefit fully. Patients often stop medication early, and alcohol can worsen other health problems.
- Fields
Medicine & Clinical Research
Public Health & Epidemiology
Psychology
- Topics
opioid use disorder
buprenorphine
treatment retention
- Grants
- 2 known grants, through May 2030
What they work on
- Test whether Behavioral Activation, Attendance Reinforcement and Peer Motivational Interviewing improve six-month buprenorphine retention, using a factorial randomized trial of 240 patients in office-based addiction care.
- Use the Multiphase Optimization Strategy (MOST), a framework for testing intervention parts separately, to choose which psychosocial components, alone or combined, belong in an optimized package to keep patients on buprenorphine.
- Apply mediation analyses to test whether each buprenorphine-support component changes its hypothesized mechanism and whether those mechanisms explain differences in treatment retention.
- Conduct online randomized trials of scalable approaches to chronic pain and physical inactivity in people living with HIV who have unhealthy alcohol use, as part of the Boston ARCH Comorbidity Center.
- Support secondary analyses of the nearly ten-year Boston ARCH cohort of people living with HIV with substance use, and mentor early-stage investigators studying pain, physical activity and functioning.
More about the research
The two projects here test practical, scalable behavioral approaches to keep people in treatment and to address conditions linked to drinking.
Why it matters
People with opioid use disorder could benefit from an efficient, ready-to-share package of behavioral supports that keeps more of them on buprenorphine. Staying on treatment is linked to fewer overdoses and deaths. For people living with HIV who drink, online, scalable treatments for chronic pain and physical inactivity may improve physical and mental functioning and fit more easily into the care of complex patients.
Known grants
From NIH and NSF research grants. Labs often have other funding we can't see.
Closest labs
Omeid Heidari
University of Washington, WA·Public Health & Epidemiology·Early-career
Design the Community-Based Opioid Treatment (CBOT) strategy and its implementation plan through interviews with patients, providers, nurses and other stakeholders, then pilot and refine it with 10 participants over three months.
Rebecca Harris
University of Pennsylvania, PA·Medicine & Clinical Research·Early-career
Identify the structures, practices, and resources of primary care Peer Recovery Specialist programs, using a program survey, direct observation at 7–10 sites, and interviews with patients, peers, and clinicians.
Rebecca Krukowski
University of Virginia, VA·Public Health & Epidemiology
Test the effect of five lifestyle components on 12-month weight loss in 608 adults taking second-generation anti-obesity medications, using a 2x2x2x2x2 factorial trial. The components are an education session, phone coaching, and digital diet, activity and weight self-monitoring.
The school
Boston University: 26 labs on PI Pages, $784M a year on research, 630 research doctorates a year.
Reach out
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