PIPages
Labs

Cande Ananth

Rutgers University-New Brunswick, NJ·Public Health & Epidemiology

Placental abruption happens when the placenta separates from the uterine wall before birth. It causes bleeding, cuts off blood flow, and deprives the baby of oxygen, which can be devastating for mother and newborn.

Fields

Public Health & Epidemiology

Medicine & Clinical Research

Earth & Environmental Science

Topics

placental abruption

pregnancy complications

perinatal epidemiology

Grants
1 known grant, through Jun 2027

What they work on

  1. Build a linked birth database of about 16 million births in five U.S. states from 2000–2016, assigning each residence daily PM2.5 and its components, nitrogen dioxide, ozone, and weather measures.
  2. Estimate how short-term air pollution and weather exposures trigger acute placental abruption using a bidirectional, time-stratified case-crossover design and distributed lag models to find critical exposure windows.
  3. Assess links between pollutant mixtures and chronic placental abruption with a cohort design and Bayesian Kernel Machine Regression, and test mediation through preeclampsia and fetal growth problems.

More about the research

Its causes remain poorly understood. About a quarter of cases appear to have a sudden trigger, and some recur in later pregnancies, which raises the question of whether environmental exposures such as air pollution and weather play a role.

Why it matters

Air pollution and weather affect nearly every pregnant woman. Identifying which pollutants, weather conditions and exposure windows raise the risk of placental abruption could inform public health guidance and environmental policy to protect pregnant women and newborns from this obstetric emergency and related complications.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Ambient Air Pollution, Weather, and Placental Abruption (APWA)

NIH · Sep 2021 – Jun 2027

Closest labs

Jennifer Stowell

University of Maryland, MD·Public Health & Epidemiology

Quantify how preconception and prenatal exposure to extreme heat and wildfire smoke PM2.5 affects risk of hypertensive disorders of pregnancy, using Cox regression within a distributed lag nonlinear framework on about 6.5 million births in claims data.

Whitney Cowell

New York University, NY·Public Health & Epidemiology·Early-career

Adapt microplastic measurement methods from environmental and marine samples to human placentas from NYU CHES pregnancies. Identify exposure sources, including changeable lifestyle factors and contamination in the delivery room and lab.

John Volckens

Colorado State University-Fort Collins, CO·Public Health & Epidemiology

Deploy a low-cost national air sampling network and analyze PM2.5 samples for trace metals and oxidative potential, the particles' ability to promote oxidative stress in cells.

The school

Rutgers University-New Brunswick: 57 labs on PI Pages, $837M a year on research, 713 research doctorates a year.

More about Rutgers University-New Brunswick

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