PIPages
Labs

Jean Hunleth

Washington University in St Louis, MO·Public Health & Epidemiology

Cervical cancer is the leading cause of cancer death in Zambia, where about 11% of people live with HIV. HIV raises the risk of developing and dying from cervical cancer.

Fields

Public Health & Epidemiology

Medicine & Clinical Research

Social Science

Topics

cervical cancer

HPV vaccination

human papillomavirus

Grants
1 known grant, through Aug 2027

What they work on

  1. Identify barriers and facilitators at multiple levels that shape HPV vaccination and primary cervical cancer prevention in rural, urban and peri-urban adolescent HIV clinics in Zambia.
  2. Translate these findings and Zambian Ministry of Health priorities into a package of implementation strategies for HIV clinics, using Implementation Mapping within the INSPIRE framework.
  3. Evaluate whether the multilevel strategy package for integrating cervical cancer prevention into adolescent HIV care is feasible, through a feasibility trial in Zambian clinics.

More about the research

Proven prevention tools exist, chiefly vaccination against HPV (human papillomavirus), the virus that causes most cervical cancers. But these tools are used little in low- and middle-income countries (LMICs), especially by girls with HIV, who face the greatest risk. The open question is how to deliver prevention reliably where staff, supplies and funding are limited.

Why it matters

Adolescent girls living with HIV in Zambia face high cervical cancer risk but rarely receive HPV vaccination. Embedding prevention into HIV clinics they already visit could close that gap. If successful, the model could be extended to HIV clinics across Zambia and adapted to other low- and middle-income countries.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Leveraging HIV infrastructure to implement cervical cancer prevention: A study to integrate HPV vaccination in adolescent HIV clinics in Zambia

NIH · Sep 2022 – Aug 2027

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Elizabeth Keating

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Describe barriers to care for injured children at health centers and district hospitals in Tanzania, the first level of medical contact, using a mixed methods approach.

The school

Washington University in St Louis: 97 labs on PI Pages, $1.2B a year on research, 365 research doctorates a year.

More about Washington University in St Louis

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