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Labs

Folasade May

University of California-Los Angeles, CA·Medicine & Clinical Research

Colorectal cancer is the second most common cause of cancer death in the United States, yet much of it can be prevented or caught early. Screening only saves lives if every step gets finished.

Fields

Medicine & Clinical Research

Public Health & Epidemiology

Topics

colorectal cancer

colonoscopy

fecal immunochemical test

Grants
2 known grants, through Aug 2029

What they work on

  1. Compare a multilevel patient, provider and health-system intervention against usual care in a six-clinic cluster randomized trial, measuring colonoscopy completion within 6 months of an abnormal fecal immunochemical test (FIT) at an FQHC.
  2. Assess the quality and challenges of carrying out the FQHC intervention to learn which parts are feasible and which matter most for colonoscopy follow-up.
  3. Measure the cost of implementing the FQHC follow-up intervention to judge whether it could spread to other safety-net clinics with low colonoscopy follow-up rates.
  4. Gather patient, provider and other stakeholder views on a planned intervention for high-risk polyps, identifying barriers to and facilitators of surveillance colonoscopy at UCLA Health.
  5. Test, in a hybrid effectiveness-implementation cluster-randomized trial, whether a natural language processing-based system that flags high-risk polyp patients and prompts recall raises 3-year surveillance colonoscopy rates, and at what cost.

More about the research

People with a positive stool test need a follow-up colonoscopy. People found to have dangerous polyps need a repeat colonoscopy a few years later. In both groups, many patients never get that next exam. Two clinical trials test multilevel interventions, which act on patients, doctors and health systems together, to close these gaps in real-world care.

Why it matters

Many patients at higher risk of colorectal cancer never complete the colonoscopy that could find and remove cancer or precancerous polyps. This applies especially to low-income patients seen at safety-net clinics and to people with high-risk polyps. Interventions shown to raise follow-up and surveillance rates could change clinical practice. Because the trials also measure cost and implementation, other health centers and health systems facing the same problems could adapt them.

Known grants

From NIH and NSF research grants. Labs often have other funding we can't see.

Evaluating a Multilevel Intervention to Increase Colonoscopic Follow-up after Abnormal Stool-based Colorectal Cancer Screening in a Community Safety-Net Setting

NIH · Sep 2024 – Aug 2029

Multilevel health system intervention to increase surveillance colonoscopy for high-risk colorectal polyps

NIH · Aug 2022 – Nov 2027

Closest labs

Sarah Miller

Icahn School of Medicine at Mount Sinai, NY·Public Health & Epidemiology

Refine the eNav Toolkit, a web app for colorectal cancer screening decisions, reminders, bowel-prep instructions and education, through two rounds of field testing with 10 federally qualified health center (FQHC) patients each.

Devin Mann

New York University, NY·Medicine & Clinical Research

Develop community health worker training modules for remote blood pressure monitoring, plus electronic health record support tools, using the Consolidated Framework for Implementation Research and user-centered design.

Elena Byhoff

University of Massachusetts Chan Medical School, MA·Public Health & Epidemiology

Measure how a multi-part food insecurity program changes clinical outcomes in Medicaid enrollees with diabetes, hypertension or depression at a federally qualified health center, using a difference-in-difference comparison with two propensity-weighted comparison groups.

The school

University of California-Los Angeles: 84 labs on PI Pages, $1.9B a year on research, 803 research doctorates a year.

More about University of California-Los Angeles

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